BDBM50346088 (1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid::4-Cyano-3-cyclopentyloxy-4-(4-methoxy-phenyl)-cyclohexanecarboxylic acid::4-Cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)-cyclohexanecarboxylic acid::4-Cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)-cyclohexanecarboxylic acid (Ariflo)::4-Cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)-cyclohexanecarboxylic acid methyl ester::4-Cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)-cyclohexanecarboxylic acid(Ariflo)::6-(3,4-Dimethoxy-phenyl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one::Ariflo::CHEMBL511115::SB-207499
SMILES COc1ccc(cc1OC1CCCC1)[C@]1(CC[C@@H](CC1)C(O)=O)C#N
InChI Key InChIKey=CFBUZOUXXHZCFB-OYOVHJISSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50346088
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant PDE4B2-mediated cAMP hydrolysis for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 288nMAssay Description:Inhibition of human Phosphodiesterase 4B from peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PDE4B (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human recombinant PDE4B by liquid scintillation counter methodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 288nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair